To needle, or not to needle?

No needle Meso is Electroporation, an alternative to Mesotherapy injections. So, what is Mesotherapy? Meso is a series of injections with a syringe containing medicines, vitamins, minerals, and amino acids. No-needle Meso is a reversed polarity current used to create temporary channels in the skin so active ingredients penetrate. What?! Let’s break it down. An electrical current pulses, that creates channels (little pores) in the cell membranes; the result: 90% of the active ingredient to penetrate. It’s said to be a pain-free alternative to injections/Mesotherapy. However, we offer the option for topical numbing cream to ensure comfort.

No-needle Meso, Electroporation, is proven to be as effective as Mesotherapy, using a syringe, at delivering active ingredients into the skin. Keep in mind; it isn’t a one-time treatment wonder. It’s recommended to have a series, anywhere from 4 to 12 treatments with both types of Meso treatments; depending on individual’s goals. However, using a syringe requires higher concentrations of active ingredients. Also, No-needle Meso results are immediate and great right before an event. When getting injections you may have bruising at the injection site. If you’re treating cellulite it may not matter because it’s easily covered. However, when you’re treating skin tightening you may have to deal with small bruises and aren’t easy to hide.

Many people choose the No-needle method for facial conditions such as skin tightening. Creams you may use at home will have some of the same anti-aging ingredients as topical medications used in Meso. Different ingredients are used depending on the condition treated. For example, when treating for skin tightening you want to increase collagen production; therefore stem cells and Vitamin C are more likely to be used. Acne treatments may include Niacinamide and Zinc; a great blend not only to smooth the skin but reduce the appearance of pores and acne scars.

A popular treatment is for skin tightening where a custom blend of serums are applied according to individual's skin type. Typical treatments consist of Vitamin C as well as vitamin-rich peptides, amino acids, stem cells, hyaluronic acid, and many more. Aging skin may respond well to Vitamin C. It protects the skin from oxidative damage and rejuvenates photo-aged skin. Due to the anti-inflammatory effects it’s works great in acne treatments. CLICK HERE FOR MORE INFO ON NO-NEEDLE MESO FOR ACNE

All treatments will begin with a detailed consultation to ensure there are no contraindications. You shouldn’t receive this treatment is you’re pregnant or breastfeeding, have a pacemaker, with the type of skin being treated. Typical symptoms are 1.) Aging skin: fine lines & wrinkles. CLICK HERE FOR MORE INFO ON ANTI-AGING 2.) Hyperpigmentation or dark spots: a result of the overproduction or collection of melanin, several possible causes. CLICK HERE FOR MORE INFO ON HYPERPIGMENTATION 3. Acne CLICK HERE FOR MORE INFO ON ACNE CAUSES & TREATMENTS.

No Needle Mesotherapy

Hours of operation:   Appointment only    M-SAT: 10-6pm & Sun: appt only

US National Liberty of Medicine independent study:


Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery.


Abstract:
Mammalian skin owes its remarkable barrier function to its outermost and dead layer, the stratum corneum. Transdermal transport through this region occurs predominantly through intercellular lipids, organized largely in bilayers. Electroporation is the creation of aqueous pores in lipid bilayers by the application of a short (microseconds to milliseconds) electric pulse. Our measurements suggest that electroporation occurs in the intercellular lipid bilayers of the stratum corneum by a mechanism involving transient structural changes. Flux increases up to 4 orders of magnitude were observed with human skin in vitro for three polar molecules having charges between -1 and -4 and molecular weights up to slightly more than 1000. Similar flux increases were observed in vivo with animal skin. These results may have significance for drug delivery and other medical applications.

Iontophoresis has been successfully employed with some polar and charged molecules. For many drugs, delivery rates in the range of micrograms per square centimeter per hour could be therapeutic, whereas significantly higher rates of delivery may be required for other drugs. In general, a 1-=fold increase in flux caused by an enhancement method is impressive, and 199 fold increase is of great interest. Thousand fold increases are rarely found. The increases of up to 10,000 fold in flux that are caused by electroporation are therefore potentially very significant and could make possible transdermal delivery of many drugs at therapeutic levels.
 

Conclusion:
Finally, transdermal flux enhancement has been demonstrated with other methods, including chemical, iontophoretic, and ultrasonic. Because electroporation is mechanistically different, involving temporary alterations of skin structure it could be used in combination with these or other enhancers. Electroporation may also be useful in other applications involving transport across skin, such as noninvasive sensing for biochemical measurement, gene therapy, and cancer chemotherapy. Together, these results suggest that electroporation of mammalian skin occurs and may be useful as mechanism to enhance transdermal drug delivery.